Cancer Races

Monday, October 27, 2008

Fwd: Epidemiology, risk and prognostic factors in mesenteric venous thrombosis.

---------- Forwarded message ----------
From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Thu, Aug 28, 2008 at 7:28 AM
Subject: Epidemiology, risk and prognostic factors in mesenteric venous thrombosis.
To: mesothelioma77@gmail.com

[1]Br J Surg. 2008 Aug 21;
Acosta S, Alhadad A, Svensson P, Ekberg O

BACKGROUND:: Epidemiological reports on risk and prognostic factors in patients with mesenteric venous thrombosis (MVT) are scarce. METHODS:: Patients with MVT were identified through the inpatient and autopsy registry between 2000 and 2006 at Malmö University Hospital. RESULTS:: Fifty-one patients had MVT, diagnosed at autopsy in six. The highest incidence (11.3 per 100 000 person-years) was in the age category 70-79 years. Activated protein C resistance was present in 13 of 29 patients tested. D-dimer at admission was raised in all five patients tested. Multidetector row computed tomography (CT) in the portal venous phase was diagnostic in all 20 patients investigated, of whom 19 were managed conservatively. The median length of resected bowel in 12 patients who had surgery was 0.6 (range 0.1-2.2) m. The overall 30-day mortality rate was 20 per cent; intestinal infarction (P = 0.046), treatment on a non-surgical ward (P = 0.001) and CT not done (P = 0.022) were associated with increased mortality. Cancer was independently associated with long-term mortality: hazard ratio 4.03, 95 per cent confidence interval 1.03 to 15.85; P = 0.046. CONCLUSION:: Portal venous phase CT appeared sensitive in diagnosing MVT. As activated protein C resistance was a strong risk factor, lifelong anticoagulation should be considered. Copyright (c) 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.

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Source: http://www.hubmed.org/display.cgi?uids=18720461
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Thursday, October 23, 2008

Fwd: Early results from a randomized clinical trial of colon $\font\ss=cmss10 scaled 1000 \hbox{J}$ pouch versus transverse coloplasty pouch after low anterior resection for rectal cancer.

---------- Forwarded message ----------
From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Thu, Aug 28, 2008 at 7:28 AM
Subject: Early results from a randomized clinical trial of colon $\font\ss=cmss10 scaled 1000 \hbox{J}$ pouch versus transverse coloplasty pouch after low anterior resection for rectal cancer.
To: mesothelioma77@gmail.com

[1]Br J Surg. 2008 Aug 21;
Ulrich AB, Seiler CM, Z'graggen K, Löffler T, Weitz J, Büchler MW

BACKGROUND:: Patients with primary rectal cancer undergoing low anterior resection are often reconstructed using a pouch procedure. The aim of this trial was to compare colon $\font\ss=cmss10 scaled 1000 \hbox{J}$ pouch (CJP) with transverse coloplasty pouch (TCP) reconstruction with regard to functional results, perioperative mortality and morbidity. As there is considerable uncertainty over the true anastomotic leak rate in patients with a TCP, the study analysed short-term outcome data. METHODS:: Elective patients suitable for either procedure after sphincter-saving low anterior resection were eligible. Randomization took place during surgery. The primary endpoint was the rate of late evacuation problems after 2 years; secondary endpoints were anastomotic leak rate, perioperative morbidity and mortality. RESULTS:: Between 21 October 2002 and 5 December 2005, 149 patients were randomized. All 76 patients randomized to TCP had the procedure compared with 68 of the 73 patients (93 per cent) randomized to CJP. Both groups were comparable with regard to demographic and clinical characteristics. Surgical complications (CJP: 19 per cent; TCP: 18 per cent) and the overall anastomotic leak rate (8 per cent) were equally distributed in both groups. CONCLUSION:: This trial demonstrated a comparable early outcome for TCP and CJP. This contradicts previous reports suggesting a higher leak rate after TCP. Registration number: ISRCTN78983587 (http://www.controlled-trials.com). Copyright (c) 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.

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Source: http://www.hubmed.org/display.cgi?uids=18720469
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Thanks very much,

Lorenz

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Have A Great Day and Enjoy Life

Cancer Races

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Monday, October 27, 2008

Fwd: Epidemiology, risk and prognostic factors in mesenteric venous thrombosis.

Thursday, October 23, 2008

Fwd: Early results from a randomized clinical trial of colon $\font\ss=cmss10 scaled 1000 \hbox{J}$ pouch versus transverse coloplasty pouch after low anterior resection for rectal cancer.

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